The ICH MedDRA Advisory Panel on Standardised MedDRA Queries (SMQs) was established by the ICH to work in collaboration with the Council for International Organizations of Medical Sciences (CIOMS) Working Group on Standardised MedDRA Queries (SMQs) to develop a tool to further support signal detection and monitoring. The Advisory Panel advises the ICH MedDRA Management Board on matters related to the development and maintenance of SMQs. The Panel also provides its recommendation to the Board to authorise the MSSO to release each new SMQ to MedDRA users.
Members of the Advisory Panel are appointed by the MedDRA Management Board and include representatives from the regulatory authorities and research-based industry of Europe, Japan, and USA, as well as Health Canada, and the UK Medicines and Healthcare products Regulatory Agency (MHRA). The CIOMS SMQ Implementation Working Group is composed of senior scientists from several drug regulatory authorities, international pharmaceutical companies, the MSSO, the JMO, and other institutions.